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Recruitment took place from July 2009 to December 2010, with follow-up completed in July 2011.

George Harrison started on an Egmond guitar and even Brian May started on one.

(A “Rosetti” branded Egmond guitar given to him from his parents) An English import company named their guitars “Rosetti”.

People routinely managed by these doctors were potentially eligible to participate if they were aged 18 or more, had a diagnosis of hypertension requiring active drug treatment according to guidelines, and consented to participate.

We excluded people who had a mean initial systolic blood pressure of 180 mm Hg or more while sitting, were prescribed three or more antihypertensives; had moderate to severe renal disease (clinical diagnosis or estimated glomerular filtration rate ), or had contraindications to angiotensin receptor blockers, calcium channel blockers, or thiazide diuretics.

But the prototype has not yet passed crash tests, because the material "will not bend like metal, but break", said the team's leader Noud van de Gevel.